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Ophthalmic Drugs for Patients with Allergic Conjunctivitis | American ...

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New ophthalmic formulations of ketotifen fumarate, pemirolast potassium and nedocromil sodium have recently received labeling approval from the U.S. Food and Drug Administration for the treatment of adults and children with itchy eyes resulting from allergic conjunctivitis. pemirolast and nedocromil are mast-cell stabilizers; ketotifen, in addition to this property, also has H1-receptor antagonist activity. Inhaled nedocromil has been available in the United States since 1993. Consultants from the Medical Letter reviewed the effectiveness and safety of new ophthalmic formulations for the treatment of patients with allergic conjunctivitis.