TO THE EDITOR: The article (1) on quinolones by Drs. Oliphant and Green was an excellent review of this important, yet often overly prescribed, class of antibiotics. We would like to commend the authors for increasing awareness of the emerging resistance to these agen...

* Met Primary Endpoint of Clinical Cure or Improvement of Infection in Intent-to-Treat Patient Population ...

Levofloxacin (Levaquin) is now approved by the FDA to treat multidrug-resistant strains of Streptococcus pneumoniae in community-acquired pneumonia (CAP), in the forms of tablets, injection, and in 5% dextrose (Levaquin Injection). Levofloxacin is a product of Johnson &...

Levaquin, also know as levofloxacin, is an anti-bacterial treatment for adults, and was recently approved by the U.S. Food and Drug Administration (FDA) for children.Levaquin levofloxacin is part of the fluoroquinolone group of oral medications prescribed to treat...

The U.S. Food and Drug Administration (FDA) recently approved an antibiotic known as Levaquin (levofloxacin), part of the fluoroquinolone antibiotic group of drugs used to fight infections, for use by children even though the drug's potential link to severe side e...

Copyright © 2008 Katie Kelley A group of antibacterial prescription drugs has recently been subject to a warning label increase by the U.S. Food and Drug Administration (FDA). The fluoroquinolone group consists of several various types of antibiotics that trea...

An Achilles tendon is a tendon located at the back of the lower leg and is connected to the heel bone. Achilles tendon rupture occurs when an individual tears the tendon, either partially or completely. Tendon rupture can occur in many instances and is caused by a...

Few long-term multicenter investigations have evaluated the relationships between aggregate antimicrobial drug use in hospitals and bacterial resistance. We measured fluoroquinolone fluoroquinolone /flu·o·ro·quin·o·lone/ (-kwin´o-lon) any of a subgroup of...

Background: Levofloxacin (Levaquin) is not approved by the U.S. Food and Drug Administration for use in children, but historical data on fluoroquinolones in children suggest an adverse event rate similar to that found in adults. Growing resistance in some bacteria tha...

A substantial number of Americans have chronic obstructive pulmonary disease (COPD) in various stages of severity. Most of these patients have stage 1 disease, according to the American Thoracic Society, which means their forced expiratory volume in one second (FE[V.s...

JERUSALEM -- Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the U.S. Food and Drug Administration has granted tentative approval for the Company's ANDAs for Levofloxacin Injection, 5 mg/mL in 250 mg/bag and 500 mg/bag (5% dextrose bags) and Le...

Treatment with oral levofloxacin is safe and effective against bacteria in the middle-ear fluid of children with recurrent or persistent acute otitis media, based on data from children aged 6 months to 5 years. ...

To the Editor: Recently, Scheld summarized factors that he considered to have an influence on the efficacy of fluoroquinolones (1). In the review, ciprofloxacin was presented as the most active fluoroquinolone against Pseudomonas aeruginosa with MICs typically two- to...

A first-time generic formulation of 750 mg levofloxacin tablets (Levaquin, Ortho-McNeil Pharmaceuticals, Inc.) has been approved by the FDA. Levofloxacin is a fluoroquinolone antibiotic and is currently indicated for various infections in adults including uncomplicate...

TABLE 1 Classification of Quinolone Antibiotics Classification Agents First generation Nalidixic acid (NegGram) Cinoxacin (Cinobac) Second generation Norfloxacin (Noroxin) Lomefloxacin (Maxaquin) ...

To determine whether fluoroquinolone fluoroquinolone /flu·o·ro·quin·o·lone/ (-kwin´o-lon) any of a subgroup of fluorine-substituted quinolones, having a broader spectrum of activity than nalidixic acid.fluor·o·quin·o·lone (fl exposure is a ris...

We determined the susceptibilities of 265 invasive isolates of pneumococci obtained during 1995 to 2001 in Hong Kong to 11 antimicrobial agents and their serotypes. Overall, 62.6% isolates were susceptible to penicillin, 20% were intermediately resistant, and 17.4%...

To the Editor: Richard Frothingham should be commended for providing added perspective on the matter of quinolone selection. His letter to the editor emphasizing the paramount importance of a well-established safety profile and documented clinical efficacy in severe ...

Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are g...

Other Problems to be Considered: Blast mycosis Cat scratch disease It is critical that hopitalized patients with suspected or documented TB be placed in appropriate isolation. This includes a private room with negative pressure and adequate air exchanges. ...

There are available dozens of antibiotics to treat pneumonia in or out the hospital, sometimes is hard even for the physician to select the best drug. To determine which is the antibiotic that suits best the physician has to determine the micro organism that caused th...

Fluoroquinolones are antimicrobials, medications used to treat infections caused by microorganisms. Most commonly used fluoroquinolones are moxifloxacin (Avelox), ciprofloxacin (Cipro), ofloxacin (Floxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), norfloxacin ...

There are more clinical types of Pneumonia and each of them is cured according to the path gnomonic mechanism which is responsible for its apparition. If the pneumonia case is caused by bacteria, less severe cases are cured with oral medication administered at home an...

Antibiotics play a very important role of modern medicine. These medications are used to fight many infections caused by bacteria. The following facts about antibiotics will help you understand how these drugs work, their possible side effects and the importance of ta...

The fluoroquinolone family is a relatively new group of antibiotics. They were first introduced in 1986, but they are really modified quinolones. The parent of the group is nalidixic acid. The majority of quinolones belong to a subgroup called fluoroquinolones, which ...

Unknown to most people is the fact that everyday foods and Herbal supplements can and do interact with popular prescription medications. I became interested while talking to my Pharmacist that my son couldn't take decongestant cold medications with his heart medicatio...

Acne Vulgaris is an inflammatory disease of the skin caused by the bacterium Propionibacterium acnes. The bacterium is an aerotolerant, nonsporeforming, slow growing anaerobic gram positive bacterium that is linked to the skin condition acne. It can also cause chronic...

An antibiotic is a drug that kills or slows the growth of bacteria. Antibiotics are one class of antimicrobials, a larger group which also includes anti-viral, anti-fungal, and anti-parasitic drugs. Antibiotics are chemicals produced by or derived from microorganisms ...

A bladder infection, or cystitis as it is technically called, is a bacterial urinary tact infection that affects the bladder specifically.Though urine contains a number of liquid waste products, it is typically sterile and does not contain bacteria. In fact, urine has...

Staph infections, at times, can circulate rapidly through communities. They definitely upset health officials because of their potential danger to harm vulnerable individuals who, for various different reasons, have suppressed immune systemsA certain strain of staph i...

Urinary tract infection, or UTI, is colonization of microorganisms in the urinary tract in such an amount and such a way that damages or symptoms are produced. When only the urethra and the bladder is affected, it is called lower urinary tract infection. When the uret...

Abstract: Warfarin is the most widely used oral anticoagulant and is indicated for many clinical conditions. Levofloxacin, a fluoroquinolone, is one of the most commonly prescribed antibiotics in clinical practice and is effective against Gram-positive, Gram-nega...

Background: Sulfasalazine and tetracyclines are effective against rheumatoid arthritis (RA). Levofloxacin, the bacteriologically active isomer of ofloxacin, is used in the treatment of infections caused by periodontopathic bacteria and facultative anaerobic bacte...

We describe the first case of failure of oral levofloxacin treatment of community-acquired pneumonia caused by Haemophilus influenzae. The strain showed cross-resistance to fluoroquinolones and carried four mutations in quinolone resistance--determining regions of ...

Urinary Infection (UTI) is a bacterial infection that affects a portion of the urinary tract. Urinary Infections affectts million people each year. The urinary tract infections are the second most common type of infection in the body. Women are more at risk of develop...

The U.S. Food and Drug Administration (FDA) recently approved an antibiotic known as Levaquin (levofloxacin), part of the fluoroquinolone antibiotic group of drugs used to fight infections, for use by children even though the drug's potential link to severe side effec...

The U.S. Food and Drug Administration (FDA) recently approved an antibiotic known as Levaquin (levofloxacin), part of the fluoroquinolone antibiotic group of drugs used to fight infections, for use by children even though the drug's potential link to severe side effec...

Urinary tract infection, or UTI, is colonization of microorganisms in the urinary tract in such an amount and such a way that damages or symptoms are produced. When only the urethra and the bladder is affected, it is called lower urinary tract infection. When the ure...

Some of the peptic ulcers may heal without treatment, spontaneously. But if they complicate the whole situation is severe, there may appear ulcer bleeding, ulcer perforation, and gastric obstruction. Ulcer bleeding manifests as: melena or black stools, weakness, ortho...

Levaquin levofloxacin is part of the fluoroquinolone group of oral medications prescribed to treat acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, noscocomial pneumonia, community-acquired pneumonia, complicated skin and skin structure i...