Abstract: A 44-year-old woman presented with a chronically draining lesion on her cheek just lateral to the nasofacial sulcus. The lesion was refractory to treatment with oral antibiotics. Physical examination revealed poor dentition, and a panoramic radiograph d...

The expansion of the semi-synthetic antibiotic preparations market and the fast growth of sales in China have propelled the development of upstream feedstock medicines and intermediates. The output of feedstock medicines, however, cannot meet the production of pr...

FDA investigators Amber Wardwell and Jennifer Menendez inspected Direct Dispensing, Miami, FL, a prescription and OTC capsule and tablet repacking and relabeling facility, on Sept. 12-16, 2005, and February 2-14 and March 28, 2006. Labeling and record information...

At any given time, more than 10 million women in the United States are pregnant or lactating, and exposing a fetus or newborn to antibiotics can pose a unique threat. Changes during pregnancy and lactation also can trigger pharmacokinetic and pharmacodynamic modificat...

Group A beta-hemolytic streptococci were once considered the major cause of impetigo; however, recent reports have indicated that Staphylococcus aureus has become the most common cause. Demidovich and colleagues conducted a study to identify the causative pathogens of...

Sickle cell disease represents a spectrum of inherited hemoglobin disorders. The pathophysiology involves abnormalities not just in red blood cells but also vascular endothelium, white blood cell function, coagulation, and inflammatory response. Known sequelae of sick...

Bulloch B, Kabani A, Tenebein M. Oral dexamethasone for the treatment of pain in children with acute pharyngitis: a randomized, double blind, placebo-controlled trial. Ann Emerg Med 2003; 41:601-608. ...

Abstract ...

Numerous interactions take place between medications and nutrients (food, beverages and/or vitamin supplements), some more significant than others.[1-3] To facilitate making rational decisions about drug therapy, the clinician should pay attention to important drug-nutr...

Applying the Evidence: Justin is a 13-year-old boy who has had sore throat, fever, and swollen glands for two days. On examination, he has exudative tonsillitis and tender anterior cervical nodes, but no posterior cervical adenopathy. What is his probability of having...

Since the 1950s, a 10-day course of oral penicillin V has been the standard treatment in patients with tonsillopharyngitis caused by group A beta-hemolytic streptocci. However, more recent studies have suggested that shorter courses of cephalosporins may produce equival...

* Context-Clostridium septicum infections are rare but often associated with serious if not fatal outcomes. Clostridium septicum infection does not appear to be associated with a single specific defect in cellular or humoral immunity. It has been associated with multipl...

Numerous interactions take place between medications and nutrients (food, beverages and/or vitamin supplements), some more significant than others.[1-3] To facilitate making rational decisions about drug therapy, the clinician should pay attention to important drug-nutr...